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KMID : 0603820120180010083
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Journal of Experimental & Biomedical Science
2012 Volume.18 No. 1 p.83 ~ p.85
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The Reason of High Prevalence of Vancomycin-Resistant (VR) E. faecium in Nosocomial Infection
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Jo Hyun-Jung
Kim Hee-Jeong
Lee Hyo-Jin
Park Gyu-Nam
Kim Min-Ju
An Dong-Jun
Chang Kyung-Soo
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Abstract
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Vancomycin-resistant (VR)-E. faecium and VR-E. faecalis were isolated simultaneously from a rectal swab of a patient diagnosed with pneumonia in an intensive care unit (ICU). The patient was treated with various antibiotics including vancomycin. Only VR-E. faecium was continually isolated from the rectal swab at one and two weeks of the treatment. Identical vanA, IS1216V, and IS1542 genes were detected in both VR-E. faecium and VR-E. faecalis isolates which showed equal resistance against vancomycin and teicoplanin, but IS1251 was not detected. VR-E. faecium showed stronger multi-drug resistance than VE-E. faecalis. This result supports the reason why VR-E. faecium is one of the major pathogens in nosocomial infections.
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KEYWORD
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Vancomycin resistant Enterococcus (VRE), E. faecium, E. faecalis, Multi-drug resistance, van gene
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